11 Disk diffusion only enabled qualitative testing of antimicrobial resistance. In the CLSI guidelines, disk diffusion or agar dilution MIC tests were used for routine clinical testing. 8 According to the laboratory diagnosis guidelines of WHO and EUCAST, 9, 10 the methods currently used for determining MICs include the agar dilution method and E-test method. 7 China-GASP was initiated in 1987 by the National Center for Sexually Transmitted Disease Control (NCSTD).

In 1990, the WHO Global Gonococcal Antimicrobial Surveillance Program (WHO GASP) was established to monitor gonococcal antimicrobial resistance (AMR) worldwide. gonorrhoeae is of great importance for the accurate treatment of patients with gonorrhea as well as to hinder the progress of drug resistance. 5 Hence, the detection of antibiotic susceptibility of N. gonorrhoeae cases have been reported intermittently. gonorrhoeae to various antibiotics decreases with time, multidrug-resistant (MDR) N. gonorrhoeae infection mainly depends on a variety of antibiotics. 2 In 2021, China reported 127,803 new cases of gonorrhea. 1 According to the WHO estimation, there were 87 million global incidents of gonorrhea annually. gonorrhoeae) is the etiologic agent of gonorrhea, a sexually transmitted infection (STI) that remains a major global public health concern.

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